Fireflies and Covid vaccines meet conspiracy theories

If you’re vaccinated, you’ll be glad to know that the Covid vaccines will not make you glow in the dark. Or else you’ll be disappointed. How you feel about it is up to you, but the reality remains unchanged.

I mention this because Newsmax’s White House correspondent tweeted that “the vaccines contain a bioluminescent marker called LUCIFERASE so that you can be tracked. Read the last book of the New Testament to see how this ends.”

The last book of the New Testament? When’s it due out? I’ll pre-order it and get back to you with a spoiler as soon as I have it in my non-glowing paws. 

In the meantime, though, let’s talk about luciferase, which does exist, isn’t scary, and doesn’t need capital letters. It’s the stuff that makes fireflies glow at night. And (because we can’t take anything for granted anymore) they glowed well before Covid vaccines were created.

Irrelevant photo: Bindweed, also known as a morning glory

Is luciferase in any of the Covid vaccines? No, but it is used in labs–and again, and was well before any of us put the letters C, O, V, I, and D together in that order. 

Let’s turn to Axandra Becker for an explanation of what scientists at the Texas Medical Center did with the stuff earlier in the pandemic–and let’s switch to the past tense to do it: It was used to “develop faster and more accurate diagnostic tests for Covid-19 as well as to analyze potential therapies and gain a clearer understanding of the SARS-CoV-2 virus itself.” 

They inserted luciferase into the genomes of the Covid, Zika, and West Nile viruses. That produced light, which made it easier to track where they (I believe that’s the viruses we’re talking about) went in a cell culture, along with what they’re reading and what they do on social media.

Okay, I’m filling in a bit where the explanation of the tracking went wavery. All it said was that they could track what was happening in them.

Admit it, my version’s more fun.

What’s any of this got to do with Lucifer? Because we can’t take anything for granted, we’ll start on the ground up and work our way up. Lucifer’s the antagonist who makes sure that there’s a market for that forthcoming book of New Testament, because without tension, no one can keep a plot rolling for that many pages and through two testaments, and antagonists are a cheap and easy way to create tension. If you open with “And God created the world and everything was nice from there on,” you have a short book.

Lucifer’s name comes from the Latin for bringer or light, or morning star, so when scientists isolated the stuff that makes fireflies (and a few other lucky creatures) glow, some clever devil named it luciferase.

Okay, we’re done with the name, now let’s go back to the vaccines: There’s no luciferase in them. None. Zero. It was used in research only. I’m multiply vaccinated and even in this post-truth era of ours I still can’t see my arm after I turn off the light. No matter what religion you do or don’t adhere to, you can get your vaccine safe in the knowledge that Lucifer–whether you believe in him or not–is not in it.

And you’ll still need a light source other than your own lovely self if you want to read in bed.

 

“A disease of the unvaccinated”

A doctor who writes as the Secret Consultant (consultant is British for a senior hospital-based doctor) says that although some vaccinated people are hospitalized with Covid, they tend to be elderly or frail or have underlying health problems. In Britain, an unlucky few otherwise healthy people will be hospitalized briefly on the general wards, but in the intensive care unit, “The patient population consists of a few vulnerable people with severe underlying health problems and a majority of fit, healthy, younger people unvaccinated by choice.”

None of them glow in the dark. Do you have any idea how helpful it would be if they did?

 

An update on needleless vaccination

Assorted groups of scientists are working on ways to deliver vaccines without using needles. One group’s working on a Covid vaccine in pill form. A trial has been approved in South Africa and will start enrolling people any day now–if it hasn’t started already.

A second approach uses a patch with spikes so tiny you can’t actually see them. These deliver the vaccine into the skin, not the muscle, which turns out to be an advantage. Muscle tissue is–well, think of it as a semi-arid zone as far as immune cells are concerned. You won’t find many of them there. Skin, on the other hand, goes into high alert when you bother it with a bunch of teeny tiny needles. The immune system wakes up, asks, “Did you need something from me?” and sends out messengers, who quickly learn to fight what looks like an invading army.

But patches have other advantages as well: 

  • They use less vaccine than a needle.
  • Babies don’t scream when they’re vaccinated–or if they do it’s for some other reason. 
  • The vaccine in patches is stable at room temperature and keeps for longer than the stuff used for needles. 
  • Anyone who can find one arm with the other one could use them. That means you could stick the patches in the mail for people to use at home.

One version of the patch has been tried on mice. Other versions–well, I don’t know what stage they’re at. The problem at the moment seems to be how to produce them in large enough quantities. 

 

Antiviral news

Scientists working at assorted universities and institutes in India have found an antibiotic that also works as an antiviral by messing with Covid’s ability to replicate.

But let’s not pretend that I can explain how it works. The best I can do is try to scare you with phrases like “amino acids . . . present in the ‘finger’ subdomain of the nsp12 protein” and  “the viral protein’s ‘palm’ subdomain cavity and the linear form of Kannurin.”

What matters is that “this approach could help us address the pandemic threat when yet another novel coronavirus emerges and medicine needs new pharmaceutical treatments ahead of the development of a suitable and widely available vaccine.” 

It’s good to know that, however screwed up humanity is, we have people among us who can figure this stuff out. 

 

Why you should take candy from strangers

A test group of 3,000 people will be sent a piece of colorless hard candy every day for 90 days. They’ll sniff it and eat it and then log onto an app to report what flavor it is and how sweet or sour it is. If the app notices any drop in drop-off in their sense of smell or taste, it will tell them to quarantine and get a Covid test.

The goal is to see if this is a way to spot Covid in otherwise asymptomatic people. 

 

How does Britain fight Covid?

Why, by pissing money out the window, that’s how. 

Okay, that’s not entirely fair. It got a vaccination program rolling early and that’s been reasonably successful, although the government followed that up by encouraging us all to run out and infect each other, since, what the hell, we’re mostly vaccinated. 

Except for the people who aren’t. Or are too frail for the vaccines to spark a good immune response. But that’s okay, because compassion’s not a big thing lately so we don’ thave to care.

But let’s go back to the money: We’re in the midst of a sleaze-valanche, and every few days we get more news about conflicts of interest and politicians giving lucrative favors to friends and donors. 

Now comes the news that we’re spending roughly £1 million a day on consultants for the test and trace system.

Those aren’t consultants as in very senior doctors. Those are consultants as in the outsiders who fly into an organization, look important, and charge a lot of money for it. They may perform priceless services. They play Tetris all day. I wouldn’t know. Either way, they do charge lots of money. On average, test and trace is paying £1,000 a day (and in a pinch a person could probably live on that), but some are making as much as £6,000 a day. In September, test and trace had one consultant wandering the halls (or working from home–again, I wouldn’t know) for every civil servant doing the same.

A year ago, it was going to reduce the ratio to 60%, although I’m not sure which side of the balance was 60 and which was 40. It doesn’t matter, though, since it didn’t happen. 

What’s the country gotten for its money? Let’s fall back on the House of Commons spending watchdog, which said test and trace hadn’t achieved its main objective, which was to cut infection levels and help the country return to normal. 

So as of earlier this fall, it had spent £37 billion in the process of failing to meet its objective. I wouldn’t mention that–I mean, what’s a few billion pounds between friends?–except that I mention the government’s incompetence so much that I thought I’d give you a quick sample of what I’m talking about.  

Fighting climate change, one misplaced city at a time

COP26–the meeting to save humanity from itself, and the planet along with it–was held in Scotland earlier this month. That presented a problem for US broadcasters, who discovered that Scotland’s geography is–well, it’s specific to Scotland is what it is. In other words, it demands a level of knowledge about a foreign country that no American can be expected to possess. 

CNN’s news presenter Wolf Blitzer opened by announcing that world leaders had gathered in Edinburgh to discuss the climate crisis. Behind him was the magnificent backdrop of Edinburgh Castle. “I’m now reporting from Edinburgh in Scotland where 20,000 world leaders and delegates have gathered for the COP26 Climate Summit,” he tweeted.

The meeting, unfortunately, was in Glasgow–a whole ‘nother city that’s rude enough to be 42 miles west of Edinburgh. 

[Late addition: I’d originally written that it’s east of Edinburgh. My thanks to John Russell for noticing that. I hope the Glasburgians had  their flotation devices close at hand until I came back and relocated them.)

The absence of punctuation is his. It may have gotten lost somewhere between the two cities.

Irrelevant photo: Flowers (some sort of geranium, I’d guess) trying to escape a neighbor’s garden.

In an effort to restore the balance, Reuters’ Jeff Mason tweeted a picture of Joe Biden walking out of his plane “in Glasgow,” although in fact he’d landed in Edinburgh. Reuters is a British-based news agency, so you might expect them to get this right, but Mason is based in the US.

I’m grateful to both reporters, because when you’re staring down the barrel of planetwide destruction you just  naturally want something to laugh about, even if the laughter does slide over into hysteria now and then. 

Before we move on, a few notes about those cities: Having landed in (check your map, please, everyone) Edinburgh, and in the spirit of climate-saving irony, Biden and his whole damn motorcade drove from Edinburgh to Glasgow.  But let’s not go too hard on Biden, the bad-optics sweepstakes were won by Britain’s prime minister, Boris Johnson, who made an appearance at COP26, then flew back to London in a private jet so he could have dinner with a climate-change skeptic at a men-only private club.

Then he announced at a press conference that COP26 had been held in Glasgow. Which he may or may not know is located in Scotland. And he may or may not be wondering why so many people in Scotland–wherever that may or may not be–want to leave the United Kingdom. 

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After listening to entirely too many US reporters, a British reporter, Channel 4’s Krishnan Guru-Murthy–who knows his Edinburgh from his Glasgow and (I’m making assumptions here) his ass from a hole in the ground–tweeted to American reporters that the city’s pronounced glas-go, not glas-gow. English spelling being what it is, I’m sure they’re grateful to have instructions. No one can assemble the damn language without them.

 

The crime and canned food report 

If crime’s what puts a country on the map, Britain can claim its spot with pride. We’re suffering from beaning attacks and the police have asked shops not to sell multiple cans of baked beans to kids. They’ve also asked parents to check their cupboards to make sure no baked beans have wandered off unsupervised.

What’s going on? Kids are dumping baked beans on people’s driveways, doors, cars, and whatever else doesn’t run away, bite, or throw a decent punch. Then they post a video. It started on TikTok, andi it has its own hashtag, as any good crime wave should.

The article where I found this included a warning that baked beans are bad for dogs, which is what makes this is so dangerous. 

For the sake of clarity, I’ve made an assumption there that you’re human. Correct me if I’m wrong.

Lord G. also led me to a source that said the tomatoes in most baked beans aren’t healthy for dogs and to another that said they’re okay for an occasional treat. If you turn out to be a dog, I guess the best thing to do is eat them in moderation .

But back to the baked beans: A beaning attack doesn’t involve a whole drivewayful of the slop. The kids spill a can or two. I’d be annoyed about it, but I couldn’t see myself calling the cops. Of course, I haven’t been beaned. Maybe I’ll change my mind if I am.

 

And in other canned food news

The holiday season’s almost upon us and Heinz–the company that makes canned soups and other prefabricated edibles–has come up with a canful of British Christmas dinner. Yes, folks, this can (or tin in British) has everything you need for the holiday–turkey, pigs-in-blankets, brussels sprouts, roast potatoes, stuffing balls, gravy, and cranberry sauce, all in the form of a soup. 

They left out the mince pies and the Christmas pudding, which is probably wise but I don’t think they can call the dinner complete without them. 

 

The possible British crisis report

You may or may not have heard that Britain’s in a semi-permanent state of possible crisis. 

Possible crisis? Yup. We keep reading about it, but from where I sit not a whole lot seems to have changed, so although I don’t think it’s fabricated, I haven’t managed to get into a full-blown crisis mood.  

What’s happening is that we’re short of truck (or if you’re British, lorry) drivers, so things that should be getting delivered aren’t–although again, most of what I look for when I do the grocery shopping is on the shelves, and what isn’t I can work around.. Still, the shortage is real, and you can blame: 1, Brexit, 2, Covid, 3, anti-immigrant politicians limiting who can come into the country and for how long, 4, government incompetence (that’s my default setting but too complicated to explain in the list format I got myself stuck with), or 5, people’s unwillingness to work for poor pay and in lousy conditions. Pick one or more, as your mood and politics dictate. As far as I can tell, all or most of them have an influence. 

What are we short of and is it really a crisis? To answer the second question first, in spite of what I said above, you’re damn right it is because (we’re back to the first question now) we could run short of fake tan any day. You know fake tan: It’s the stuff that if you’re white you slather on yourself so you’ll look like you risked cancer to get a skin color you like better than the one you came in.

Or maybe you don’t slather it on yourself. I’ll confess to never having used it, but isn’t it fascinating that a culture which still–with apologies for the generalization–looks down its nose at people with darker skin is addicted to slatherable skin goop because people with lighter skin want to be darker? 

The reason for the shortage is that manufacturers are having trouble getting ethoxydiglycol, dihydroxyacetone, and erythrulose. Possibly because of how hard they are to spell. 

If this plays out as predicted, yes, we’re in serious trouble over here. If you live elsewhere and have friends or relatives in Britain, send fake tan! 

Before I leave the topic, though, we need two truth-in-reporting moments: 

1) Although we genuinely are short of delivery drivers, and the government genuinely is incompetent and also at the moment gloriously mired in sleaze reports (we’re in the midst of a sleaze-valanche and I’m having a wonderful time, thanks; it more than makes up for the fake tan crisis), neither of these seems to be the source of this particular shortage. I can’t rule out Covid, though. 

2) We have a crisis that’s getting less press than the driver shortage, and that’s an overwhelmed health system. This is only partially a Covid problem. The National Health System has been underfunded for years, all in the name of efficiency, and also partially privatized (also in the name of efficiency, and setting the NHS up to fail can be used to justify that). It’s also been disastrously reorganized,. And not enough doctors and nurses have been trained. Many are getting ready to retire, and already hospitals are reporting that they’re dangerously understaffed. I’d ask you to send trained medical people as well as fake tan–as a nation, we’ve relied on raiding the world for their trained medical people–but since we hate foreigners these days, not many of them would be eligible to work here. 

 

What’s the best way to honor veterans?

In Cheshire, two politicians (okay, one of them’s a former politician) who are both veterans decided that the best way was to hire a 7.8 ton tank and drive it through town to the local Remembrance Day event, where they forgot to set the handbrake–the thing Americans call an emergency brake. That allowed the tank to roll into the remembrance garden’s gates and smash hell out of them, thereby ensuring that even if other veterans are forgotten, the two of them will be remembered.

The tank rents for £950 a day, in case you want one. 

 

And finally a sensible story

As vaccine mandates push the reluctant to let themselves be vaccinated, a new idea’s entered the lune-a-sphere: getting that vaccine out of your body once it’s been put in. People are being advised that they can give into the mandate and keep their jobs but in the privacy of their homes make sure their bodies stay virginal and unsullied.

How do they do that? Well, according to one anti-vaxxer, who’s gotten enough views on TikTok to draw attention from the mainstream media, they take a detox bath of water, baking soda, epsom salts, and bentonite clay. Then they add a cup of Borax.

That soaks out radiation, poisons, and nanotechnologies.

What nanotechnologies? The liquidized computers in the vaccine that are turning us all into transhumans. 

How do the vaccine makers do that? They disassemble one of those old room-sized computers, put it in a blender, and add it to the Covid vaccine vats. 

Or–okay, I might possibly have made up the method, but we live in a post-truth world. Who’s going to challenge me? 

According to the experts, unvaccinating yourself is right up there with unringing a bell. Between the time the needle goes into your arm and the time you reach your car (assuming you have a car, and that you came in it) the vaccine will have started to work. 

It’s hard to pick a single element out of this and crown it the most controversial, but let’s try. We’ve got the claim that people can soak out a vaccine out of their bodies. We’ve got the claim that the vaccine (which one? does it matter?) activates radiation (no, don’t ask me), and we’ve got the claim that it contains a liquified computing system that will turn us into transhumans. But on an immediate damage-to-the-body level, the most controversial element surely is soaking in Borax. 

Now, Borax has its uses, and if you want to kill ants and cockroaches, it’s good stuff, but but soaking yourself in it isn’t recommended. It can irritate your skin and eyes. I’m not sure what it does to ants and cockroaches, but I’m sure it’s nothing nice. They haven’t offered any testimonials for the stuff. 

My advice? Dress warm, friends, and carry an umbrella, because it’s crazy out there.

Other People Manage

Other People Manage is a novel about the pain we carry and the love that gets us through the day. The publisher, Swift Press, describes is as “a powerful, moving, engrossing story of two women whose lives together start with an unexpected and terrible tragedy, and whose love for each other and their family endures the joys, disappointments and triumphs of life. This is that rare thing in the publishing world: an extraordinary book that was not bought for a six-figure advance in a twelve-way auction, but that will have a huge impact.”

It also happens to be mine, and although it’s not the first one I’ve published I’m incredibly excited about it. It will be available in April 2022, and (not that I’m trying to sell you anything, you understand) you can pre-order it from Waterstone’s. That’s a British bookstore, but it’s open minded enough to ship to other countries.

The reason I’m telling you about it now is that pre-orders can give a book a real boost and I’m shamelessly trying to do that for this one. I think (she said modestly) that it’s good, and I want to get it out into the world where people can find it.

You can find an early review here. And if you’re a reviewer yourself, you can get a copy from NetGalley. If you have any trouble with the link, let me know–I can get you in through the back door.

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Next Friday, we’ll resume our regularly scheduled programming with a post about Britain. Or possibly the pandemic. In the meantime, thanks for you patience.

How a British town becomes a city

The English language plays tricks when it travels from one country to another, so if you asked me to define a city I’d have to ask you where the city is. Or where you are. 

Some days, I’d have to ask you where I am.

In the US, it’s fairly simple: A city’s a place where a lot of people live. How many? Um, yeah, no one’s drawn a clear line to separate it from a town.

In Britain, though, a town has to do more than get big to become a city. And in some cases, it doesn’t even have to get big.

 

The informal definition

Most people in Britain will tell you that a city has to have a cathedral, although one article I read claims a university will do just as well, and a few people think the town has to gather up a lot of people and convince them to live there.

But in Britain there’s a difference between people thinking of a place as a city and the place formally being one. To really be a city, the place needs the queen or king to wave a magic city-making feather over it.

Irrelevant photo: a begonia

Yes, really–except for that business with the magic feather. Because of course the queen or king has the final say over how many cities the country has. If they didn’t, for all we know every cluster of houses would dance around singing, “We’re a city. Look! We’re a city.” Order would break down. Trains would stop running. Long-established recipes would cease to work. 

Imagine Britain without its bakewell tarts and victoria sponges.* 

So yes, of course officialdom wants to put some limits on the number of cities.

Mind you, the king or queen doesn’t actually make the decisions about which town to citify. Officials do the choosing, but it’s the monarch who waves that feather, presumably while looking entirely serious about it.

Just to confuse the issue, though, any number of towns are governed by bodies that call themselves city councils. 

Why do they do that? Possibly because someone has delusions of grandeur and possibly because the language is at war with the country’s endless formalities. 

 

The formal process

Britain’s home to 66 officially recognized cities–50 in England, 6 in Scotland, 5 in Wales, and 5 in Northern Ireland. Not all of them have cathedrals. The belief that they had to comes from a time when building a cathedral really did make you a city. This led to small places like Truro being cities while much bigger industrial centers like Birmingham and Belfast weren’t.

In 1889, Birmingham became the first cathedral-less place to be recognized as a city, and these days you can leave all that stone in the ground and bid for city status through the Ministry of Housing and a Few Other Things. It’s less romantic than building a cathedral, but it’s cheaper and it’s easier on the fingernails.

There’s a catch, though: You can only apply on special occasions, when the Ministry opens up bidding to mark some occasion: the millennium, the golden jubilee, the silver jubilee, the arrival of a new kitten. Outside of those special times, towns have to shut up and wait.

What’s a jubilee? In dictionary terms, a celebration of anything from emancipation to becoming a king or queen, but in this context it has to do with Liz having become a queen some number of decades before. Or more accurately, the queen—something Britain as a whole takes seriously, even if not every single individual who lives here does.

 

How big does a city have to be?

Not always very. The U.K.’s smallest city is St David’s, which has a whopping 1,600  residents–not all that many more than the village I live in. It earned its status in 1995 to mark the queen’s 40th anniversary, and it was chosen because of its role in Christian heritage.

Yeah, the monarchy takes that Christian heritage flap seriously. It has to. If it didn’t, what’s to justify someone being the monarch instead of just one more citizen?

Part of the argument in its favor, though, was that it had a cathedral, so people already thought of it as a city. 

In practice, being big doesn’t guarantee official status as a city, and neither does being thought of as a city. London contains two cities–the City of London (called the City, as if the planet didn’t have any others) and the City of Westminster. But London itself itself isn’t, officially speaking, a city.

If you get dizzy, just sit down and rest a while. We’ll be here when you come back.

 

Mayors and cities

Most city councils (whether they govern cities or towns) will appoint a mayor, who does ceremonial stuff and shows up at special occasions in eye-catching and wildly outdated clothes, including gold chains that outdo anything a celebrity ever turned up in. If the queen (or king, as the case may be) has waved a different magic feather over the locality, the mayor may turn into a lord mayor. This will make no practical difference in his or her ability to climb stairs, lose weight, or push a car out of a snowbank. 

But having a lord mayor doesn’t make a place a city.

Sorry. Like I said, different magic feather, different result.

How do you address a lord mayor? You say, “Lord Mayor.” Or you say, “My Lord Mayor.” Or if appropriate, “Lady Mayoress,” or, “My Lady Mayoress.”

You do not laugh while you’re doing any of that upon pain of being banished from the event and left giggling hysterically on the sidewalk.

In a different category of officialdom, many towns and cities have an elected executive mayor, a title that sounds less impressive but comes with political powers, which ceremonial mayors lack. 

Having an executive mayor also doesn’t make a place into a city. 

 

Can a place stop being a city?

Yup. Rochester accidentally lost its status in 1988, when it reorganized its government structure and–well, you know how sometimes the cat jumps on the keyboard and your entire life disappears and next thing you know you no longer exist? It was like that. 

By way of demonstrating how important it is to have city status, four years rolled past before anyone noticed the city was no longer a city. 

It still hasn’t gotten its status back.

 

What are the benefits of being a city?

None, at least according to Professor John Beckett“There never have been any privileges. It’s always been a status thing, nothing more. There’s nothing to stop places declaring themselves a city–Dunfermline did it.”

The whole system, he says, “makes no sense” and just “gives a bit of patronage to government”.

Dunfermline declared itself a city in 1856. It figured that since it had been Scotland’s capital for 400 years, it had the right. The idea of it as a city never caught on, though, and it’s planning to bid for genuine city status when the queen’s platinum jubilee rolls around, in 2022.

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* A victoria sponge isn’t something you wipe the kitchen counter with. It’s a cake-ish thing, as is a bakewell tart, although I’m stretching the definition of cake pretty thin in saying that.