Is a universal coronavirus vaccine a pipe dream?

Scientists are in the (very) early stages of working out a universal vaccine against coronaviruses–one that would block not only Covid’s existing and future variants but any new coronaviruses that emerge.

Okay, let’s call that a possible vaccine. It could easily not work out, but on the other hand no law of nature says that it can’t. Scientists have been doing the next-to-impossible a lot lately. I’ve started to take it for granted. 

IMG_0082 (1)

Irrelevant photo: A camellia bud, stolen from an old post because I’m trapped in WordPress’s horrible new editing program and haven’t found a way to drop in new photos at full size. I had a way to avoid the new system, but they’ve blocked it.  

They can approach the task in two ways. One is to make a mosaic vaccine. That has nothing to do with Moses–you know, the guy with the stone tablets. It’s from the word for those tiny pieces of colored tile that make up a picture. The vaccine takes particles from several Covid variants or other coronaviruses and sticks them onto a nanoparticle–a very tiny biological structure made up of proteins. Think of it as sticking some olives on a toothpick.

Or don’t. It’s your mind. I’ll never know. But if you do want to go out on that imaginary limb with me, watch while I saw it off behind us: We’re going to take that toothpick with its olives and drop it into the martini of your immune system.

Thwack. That was the sound of us hitting the ground, olives and all.

It would make a nice lullabye, don’t you think?

Now that we’ve dusted ourselves off, we can let our immune systems figure out what those bits of virus have in common and arm itself–and us–against that.

When this was tried in mice, their immune systems created a broad range of neutralizing antibodies. And creating neutralizing antibodies is the main goal of any vaccine.

Mice–as no doubt you already know–are not humans. They’re also not martinis, so this may not transfer seamlessly from them to us. But it holds some promise.

If you’ll let me brush those twigs out of your hair, we can go on.

The second approach has the scientists looking for features that are common to all coronaviruses. That could mean analyzing their genetic sequences to see where they overlap. It could also mean looking for immune cells that react to either all coronaviruses or to a number of variants, and then mapping the parts of the virus that they target. After that, all that’s left is to create a vaccine aimed at that spot.

Nothing to it.

Those of you who don’t drink will be relieved to know that no martinis are involved in this approach.

Now I’ll throw cold water on the whole project and tell you that scientists have been trying to come up with a universal flu vaccine and a universal HIV vaccine for years. The candidates have been safe but not impressively effective. Still, Covid doesn’t mutate as quickly as either HIV or the flu.

Yes, really. In spite of everything we’ve been reading about variants. This is what’s called slow mutation. 

So no one’s offering guarantees that this will work, but it’s a bright spot on the horizon. 

The horizon, unfortunately, is a good long way away.

Policy-type stuff

An international survey of how countries handled the pandemic shows that autocracies and democracies did equally well and equally badly, as did rich countries and poor countries and countries governed by populists and countries governed by technocrats. In other words, none of those were decisive factors.

Lockdowns of one sort or another do break the chain of infection, but they’re not universally successful. If the population doesn’t trust the government, they don’t seem to work. (I’m stretching the study’s conclusion a bit there. It sounds more tentative about it.) Economic support may make lockdowns more effective. (“May”? I can’t imagine the part of the world where making sure people who can’t work can still eat and pay their rent wouldn’t help. Never mind. It’s not my study. They’re not my conclusions.)

Some countries with strong scientific capacity and healthcare systems have responded badly, and some countries with far less (Mongolia, Thailand, Senegal) have both kept their people healthy and the economy running. 

Some countries (Taiwan, Vietnam, and New Zealand get a mention) did well in controlling the first wave and kept control from there on. Others did well in the first wave but the waves that followed swept over them. 

I’ll get out of the way now and let the people involved in the study have the last word:

“While our work has tracked individual governments’ responses, it is clear that exiting the pandemic will require global cooperation. Until transmission is curtailed throughout the world with restrictions and vaccinations, the risk of new variants sending us back to square one cannot be ignored.”

In other words, we’re all in this together. Even when we don’t act as if we are.

*

So let’s check in on a country that’s managed well and hasn’t gotten a lot of publicity. 

Before it had its first Covid case, Iceland had a testing system and a contact-tracing team, ready to go to work as soon as they found their first case. They put everyone who tested positive into isolation and traced their contacts. The word one of the people involved uses, with no apology, is aggressively.

Isolation–as least in Reykjavik–is in a hotel that was converted for the purpose. In response to which the staff walked out. The man in charge (I have no idea what his title is–sorry; let’s call him Gylfi Thor Thorsteinsson, since that’s his name) coaxed them back. They work in full protective gear. Thorsteinsson at least goes into people’s rooms to keep them company.  I assume many of the others go in as well, but the article I read didn’t say. In the past year, the hotel’s taken care of more patients than all the hospitals in Iceland rolled into one.

After Iceland got its first wave under control, they closed the hotel. Then they immediately had to reopen it when two tourists who’d tested positive went a-wandering. And by immediately, I do mean immediately. They just had a goodbye party for the staff when they had to say hello again. 

Now anyone who lands at the airport is tested and put into quarantine. As a result, Iceland is a country where people can go to bars, eat out, and generally wander the world without masks, as if life was normal. Not because they’re risking their lives and other people’s but because it’s safe.

At one point, someone carrying the UK Covid variant slipped through the net and spread it to a second person, who went to work in a hospital and in case that wasn’t bad enough went to a concert with 800 other people, who all crammed into the bar during the intermission. 

Whee. Viral playtime.

Within hours, the tracing system had contacted every one of them. Within days, they’d tested 1,000 people, finding two cases, and they were taken to the isolation hotel. 

And that was it. The virus was contained. 

Why has Iceland been so successful? Thorsteinsson said it’s because “it has been the scientists making up the rules, not the politicians. That matters. They know what they are talking about, the politicians do not.”

The prime minister, Katrin Jakobsdottir, seconded that. 

I think it’s important for a politician to realize what is politics and what needs to be solved by scientific means. It’s my firm belief that we need to listen more to the experts.”

 

A short technical rant

WordPress in its wisdom has blocked the back road that once allowed me to use its manageable Classic Editor, so I’m now trapped in the new one. If anyone knows how to size photos (or knows a back road), pleasepleaseplease let me know. Thanks.

What might a vaccine mean? It’s the pandemic news from Britain

Now that we (may) have a vaccine, let’s talk about what it could mean. Because it’s not all Problem Solved. We’ve had a little time to feel good, so now we get to look for monsters under the bed. They may turn out not to be there, but let’s take a look while it’s daytime. Just to be safe.

Potential monster number one: We don’t know yet whether the Pfizer vaccine will keep people who’ve been exposed to the virus from spreading it. It may, but it’s also possible that it–or any other vaccine–will keep people from getting sick but not keep them from being silent spreaders. That would mean we can’t end social distancing and can’t burn our masks.

I can’t tell if those are beady little monster eyes I’m seeing or if it’s the buttons I lost a couple of years back.

I really should clean under there more often.

Potential monster number two: If the Pfizer vaccine is the one we all go with initially, logistical problems are a certainty. It has to be kept at an insanely cold temperature–minus 70 C. That’s minus 94 F. Not even forty years in Minnesota prepared me to understand how cold that is. The worst I saw was minus 40 F., and I think that counted the wind chill. It was cold enough to freeze any thought other than How do I get indoors but wasn’t cold enough to impress this vaccine.

That’s going to be more of a problem in countries without a well-developed infrastructure and without the money for a supply of–um, what do you use to keep a drug at that temperature? Something with more insulation than your average lunch bucket. 

Irrelevant photo: mallow

Potential monster number three: How much of the vaccine can be produced how quickly, and at what cost. And how much of what’s produced will be available to poorer countries? Because until the virus is under control everywhere, it won’t be fully under control anywhere. 

Potential monster number three and a half: Initial supplies will be limited, and the British government’s drawn up a tentative list of what sort of people will be priorities, but no country’s likely to have enough doses for all of its population. So what does that mean?

Say a vaccine protects 70% of the people who get it. (This is based on an article that came out before the preliminary Pfizer announcement of 90% protection, so the numbers will change but the structure of the problem won’t.) If 70% of the population is vaccinated, which is unlikely at first, 49% of the population will be immune.

Why 49%? Why not 49%. It’s a nice number–just off balance enough to be convincing. What it’s not, though, is enough to give us herd immunity. If the priorities for vaccination are the oldest people, the most vulnerable, and (please!) the front-line workers, that will still mean that younger healthy people need to maintain social distancing, wear masks, and generally continue to live the way we’ve been living. And people who’ve been vaccinated probably will as well if the vaccine doesn’t keep them from being contagious. Otherwise they’ll endanger both the 51% of vulnerable people who haven’t been protected. And (I know, I keep saying this) younger people are more vulnerable to this than we tend to think, so they’ll endanger them as well.

But it’s not all monsters and buttons and dust bunnies under the bed. We’ve got some potential monster-slayers too. 

Sorry, I don’t mean to get bloodthirsty about this. If you’re squeamish about killing a virus, take heart: A virus is not actually alive. Or else it is. This is something microbiologists argue about. It all depends on how you define life. Either way, though, it’s them or us. It’s enough to drive even the most dedicated pacifist to sit down and have a good long think.

So, potential monster-slayer one: On a very long-term basis, it’s possible that young kids who catch the virus but don’t get sick will build up a generational semi-immunity and Covid will eventually become just another cold. It’s possible that the four coronaviruses that cause colds started out like Covid. One of the four left cattle and discovered humans around 1890–the same year as what’s been thought of as a flu pandemic but might, in hindsight, have been a cousin of Covid. 

It’s possible. It’s also possible that all that is wrong. And of course most of us have to live long enough and emerge healthy enough for that to matter.

Potential monster-slayer two: More immediately, with the introduction of a vaccine, testing and tracing come into their own. They’re most effective when case numbers are relatively low–much lower than Britain has at the moment– because a country needs to track and quarantine every case. A vaccine could put us in a position to use testing and tracing well. 

Of course, even if you only have three cases, you still need a competent track and trace system. I’m not sure ours is up to the challenge of three cases yet.

Early in the pandemic, South Korea used track and trace well and Joshua Gans of the University of Toronto says, “We need to all become South Korea as quickly as possible.”

That will mean ensuring that quarantine actually works. Estimates of the percentage of people in England who fully self-isolate when they’re supposed to are low (11% according to one study), and the situation isn’t helped by the lack of genuine financial support. Some people can’t afford to stay home. Others, presumably, don’t take it seriously.

One problem with testing has been that the fast tests are less accurate than the slow ones. A test that is 90% sensitive will miss 10% of positives. But don’t despair. Baffling math may save us here. “Two tests five to seven days apart are 99% sensitive in finding you positive–if you actually are,” according to epidemiologist Tim Sly.

No, don’t ask me. They’re numbers. I can’t explain why they do what they do. The main thing is not to let them sense your fear.

The recommendation is to test people frequently–frontline workers, people who fly, people who breathe. Some of the rapid tests can spot people who are actually transmitting the virus, not just people who have symptoms. 

So we’re not ready to have a massive, maskless, indoor party the day after the vaccine arrives. Or maybe even the year after the vaccine arrives. Put away the confetti. Take a bite of the ice cream, then shove it back in the freezer.

But the picture is changing, and even though we have a government that’s elevated incompetence to an art form, I’m hopeful.

Pesky science and contact tracing: It’s the pandemic news from Britain

A former Conservative Party leader, Iain Duncan Smith, accused Boris Johnson of “giving in” to the government’s scientific advisers when he declared a second lockdown. 

Those damn scientific advisors. You can’t turn your back on them for a minute. It’s all just science, science, science. 

So what have those pesky scientists done lately? 

Some have demonstrated that masks don’t deprive you of oxygen. Yes, they already knew that, but the rumor that they do has a life of its own, so a few of them went ahead and rigged up a clutch of people with portable pulse oximeters (the measure blood oxygen levels), and guess what: They found no signs that any participant was short of oxygen. 

In other words, they’re saying you should wear a mask. You’ll still be able to breathe.

Pesky damn know-it-alls.

They’re also developing an overwhelming number of possible vaccines–more than I can keep up with–and identifying existing drugs that hold out the hope of treating Covid well enough to at least prevent hospitalization. But stay strong, people. We mustn’t give in to them. We’re doing just fine by our own ignorant selves.

*

We haven’t heard much drum-beating lately about Britain’s world-beating Covid app–the one that was going to save us all–but every so often an article surfaces about what’s gone wrong with it. The latest is that it was set at the wrong sensitivity level, so it missed notifying thousands of people that they’d been in contact with and infected person, and it stayed at that setting for a month. A government source said a “shockingly low” number of people were sent warnings. 

*

Someone working in Britain’s business secretary’s private office tested positive for Covid and the rest of the office went into isolation. But the business secretary himself, Alok Sharma, went to South Korea and even after he heard of the positive diagnosis held meetings there . 

He hadn’t had close contact with the person who tested positive, he said. 

They had a meeting four or five days before, the papers say–and people are contagious before symptoms begin. 

Sharma hadn’t “been told to isolate by NHS test and trace,” a spokesperson said.

Well, no, I don’t expect he had been. The test and trace system is notoriously nonfunctional.

Sharma tested negative before he left for the trip and again when he arrived, someone the spokesperson said, not mentioning the test’s percentage of false negatives or its inability to pick up pre-symptomatic cases reliably.

*

Before England went into lockdown, the universities minister (hands up: who knew Britain had one?) urged university students to stay where they were for the duration of the lockdown. Some uncounted many headed home anyway. 

Most of them are taking classes online anyway. 

*

Michael Gove, the cabinet office minister, and Robert Jenrick, the communities secretary, gave out assorted wrong information on what people could and couldn’t do under the new lockdown rules. There’s no point in repeating misinformation, so let’s just say that it hasn’t helped. They apologized very nicely, and in fairness the new lockdown was hauled out of the flatpack so quickly that the government only had time to put half the screws in place. We’ve been asked not to rest heavy objects on it until November 15.

Still, I don’t think they’ll be letting any ministers out on their own for a while.

*

The Department for Education has outsourced the work of advising schools on how to handle Covid. Until recently, this was done by clinicians from Public Health England, who advised, did spot checks, followed up, and advised further. Then in September they were replaced with a call center whose workers read from a script. One teacher was told to send thirty-two students home.

Why thirty-two? he asked.

The call handler didn’t know. 

*

At the end of October, Boris Johnson promised England that we’d have Covid tests we could read ourselves. Better yet, they’d give us a result in ten to fifteen minutes. They’d work on presymptomatic people, asymptomatic people, semisymptomatic dogs, cats in all states of symptomosity, and ham sandwiches–in short, everyone and everything. Including–this being England, a nice cup of tea.

People could be tested, know they were safe, and go on with normal life. And the would still be warm enough to drink.

The government bought 20 million of tests. 

Unfortunately, the maker’s website says the tests aren’t meant for people without symptoms and are meant to be read by a health professional. 

Step away from that tea, please.

*

Just in time to beat lockdown, a couple got married, joined their last names, and became Mr. and Mrs. White-Christmas.

Seriously. Tilly Christmas and Kieran White. I doubt they had any arguments over whose name would come first.

https://www.bbc.co.uk/news/uk-england-dorset-54822289

 

 

Are clothes essential in a pandemic? It’s the news from Britain

In a protest over the Welsh government’s ban on stores selling nonessential goods during the current lockdown, Chris Noden turned up at a supermarket in nothing but his undies and tried to shop while his wife followed along behind and recorded everything on her phone. A store employee kept him from going in, and as soon as Noden got him to admit that clothing was essential, he decided he’d made his point and left.

“I understand they have to control crowds in shops,” he said later, “but if someone really needs something or an item, what is it to stop them? They are actually blocking these aisles off with sweets, chocolate, bottles of vodka, whisky, lager, they are blocking it off with all nonessential items, essentially. I don’t know what is essential or not, it is a bit mad, like.”

What he’s talking about is that supermarkets blocked off areas selling nonessentials.

It’s true that he does seem to get stuck on a thought and repeat it, but he managed to make his point all the same. It’s also true that he didn’t just wear his undies. He also wore shoes, socks, a mask, and a tattoo. 

The essentials, essentially.

My thanks to Ocean Bream. If it hadn’t been for her, I’d have missed this and what a tragedy that would’ve been.

*

Irrelevant photo: If I remember right, this is a thistle. Gorgeous, isn’t it?

Meanwhile, on October 29, British papers reported that nearly 100,000 people a day were catching Covid in England. That’s based on a study by Imperial College London, which also estimated that the rate of infection was doubling every nine days. That takes us close to the peak of infections last spring, although the death rate for people who have severe Covid is down from last spring, probably because a lot’s been learned about how to treat it.

Every age group in every region shows growth in the number of cases. In London, the R rate–the number of people each infected person passes the disease on to–was 3. The Southeast, Southwest, and East have an R rate above 2. On a national average, it’s grown from 1.15 to 1.56.

Regional lockdowns in the north may have slowed the spread, although they don’t seem to have stopped it. The government is frantically trying to avoid a national lockdown.

*

But it’s all going to be okay, because the government has plans to do a Covid test on 10% of England’s population every week, using tests based on saliva, which are easier to manage than the current ones and give a result in thirty minutes. The plan is ambitious, headline-grabbing, and badly thought out. In other words, pretty much what anybody who watches this government would expect. 

The idea is that local directors of public health will “be eligible to receive” tests “equivalent to” 10% of their population. Which is a roundabout way of saying that’s how many tests they’ll get, but with a small escape clause in case someone needs to wriggle through the definitions of equivalency and eligibility. A properly motivated politician could emerge from that snarl rumpled and stained but still claiming victory.

In a moment of heroic bad planning, the project was launched without anyone talking to the local governments and health officials whose cooperation it depends on. 

What will the program expect of them? The head of the test and trace program, Dido Harding, said local authorities will “be responsible for site selection and deployment of [lateral flow] testing in line with their priorities.”

Lateral flow? Oh, come on, you know that. It’s what happens when things flow laterally, which is to say sideways.  

Did that help? 

I thought it would.

But it’s even better than that, since we’re translating. Things will flow not just sideways but also in a line with their priorities, which we can assume run sideways.

Whose priorities? I’m not entirely sure. Local governments’, probably, and they’ll get to choose their priorities by picking Option A or Option A. That way it’ll be their fault if Option 3 turns out to have been the obvious choice. Honestly, anyone would’ve been able to see it.

And no, I didn’t add that “[lateral flow]” business. That was some desperate reporter trying to condense a document full of waffle and bureaucro-speak.

So are local people wild about the program? Not demonstrably.

An anonymous director of public health said, “There is no point in testing large numbers of the population unless you do something with the results. We really, really want to improve testing and tracing, but once again this is the wrong way to go about it.”

Another public health official–a senior one, whatever that may mean, and also  anonymous–said, “We don’t know who does the contact tracing or how the workforce [to carry out the tests] is resourced. [That means paid for–and this is my addition.] We are trying to work out how this fits with the test-and-trace strategy with PCR testing and how any positive results are followed up and people are isolated.”

PCR testing is the kind that’s currently being done–the slower, more invasive kind of test.

And yet another anonymous senior public health official said, “They have come to us with a proposal that is poorly thought through. It is not clear what the cost is or the amount of work involved and there is nothing about contact tracing.”

As for the existing test and trace system, it might just meet its target of testing 500,000 people a day by the end of the month, but it’s done it by getting the results back to people more slowly than promised–sometimes at half speed–and bungling the tracing element. One in five people who test positive and are referred to the tracing side of the system are never heard of again. They’re abducted by flying saucers and held out of range of cell phones–or if you’re British inflected, mobile phones, whose name only promises that you can move them around, not that they’ll work where you so foolishly brought them. 

Are those lost people isolated while they’re there so they can’t pass on the virus? That’s the thing: We don’t know. But if you will get yourself abducted by flying saucers, you can’t blame Dido Harding for it, can you?

It’s also possible that the system’s missing more than one in five people. It depends when you wandered into the movie. Another article says less than 60% are reached, so that would be two out of five. 

I think. 

Oh, never mind the specifics. It’s all just a lovely, poetic way of saying the program’s a mess.

One article I found included an example of the kind of snafu that happens in the vicinity of the test and trace system: a small war over who’d pay for a portable toilet at a mobile testing station. The central government (I’m reasonably sure that would be the test and trace program itself) refused. Because they’re test and trace, after all, not test and toilet. That left two local entities playing hot-potato with it for days. In the meantime, the station couldn’t be set up, because no matter how little you pay people, and even if you put them on zero-hours contracts, they will want to pee eventually. 

*

However hot that potato was, though, it’s a small one. Here’s a considerably larger one:

After advertising for people with a health or science degree (or an equivalent something or other) to work with experienced clinicians  in the English test and trace system, Serco–a private contractor–instead upgraded a bunch of people who were already working there, people with no relevant degrees or experience and who were working for minimum wage. That’s £6.45 an hour if you’re between 18 and 20 and £8.72 if you’re over 25.

You may have noticed that some years are missing there. That’s okay. Most of the callers are in the 18 to 20 group.

The job as originally advertised–the one the minimum-wage folks got moved into–was supposed to pay between £16.97 and £27.15 an hour. The people who got moved into the job are still working for minimum wage. 

That’s called upskilling. It’s not called up-paying. 

We can’t exactly say they weren’t trained. They got four hours of power-point training, an online conversation, a quiz, some e-learning modules (doesn’t that phrase send a thrill down your spine?), and some new call scripts. 

“It’s been an absolute shitshow,” one highly anonymous caller told a reporter. The callers are talking to people who’ve lost family members. People who cry. People who are in pieces. And the callers’ training manual says things like, “If somebody’s upset, be patient.” 

It leaves some of the callers themselves in pieces. They’re young. They have no training to help them deal with this. They’re in over their heads and they know it. 

I can’t imagine the system’s working any better for the people they call.

Somewhere in between advertising the higher pay level and giving the job to people at the lower one, the Department of Health and Social Care made a decision to split the job in two. The first set of callers would make the initial calls and then “qualified health professionals” would follow up. 

But Mr, Ms, of Mx Anonymous says, “There is no other call by a trained clinician.” The callers read out a list of symptoms, refer anyone who needs medical advice to 111, the Covid hotline, and only if they decide that there’s an immediate risk do they pass calls to a clinical lead. 

So this is, on average, a 20-year-old being asked to decide if there’s an immediate risk. No disrespect to 20-year-olds–I was one myself once–but you don’t have a lot of life experience to draw from at that age.  

Have I mentioned that the test and trace service is privatized? And that to date it’s cost £12 billion–more than the entire budget for general practice. More than the NHS capital budget for buildings and equipment.   

Which is one reason that a group of doctors have called for the money to be diverted to local primary care, local NHS labs, and local public health services. Local, local, and local. 

I’m not expecting anyone to listen to them.

*

And so we don’t end on a completely sour note, Taiwan has marked 200 days without a domestically transmitted Covid case.

Its success is due mostly to reacting early and sanely: establishing coordination between government departments; emphasizing the use of masks; quarantining new arrivals. It didn’t hurt that both the strategy and communications with the public were led by experts.

It’s a radical concept, but it just might work.

Movies, apps, and money: It’s the pandemic news from Britain

 

Boris Johnson responded to the news that a movie chain is closing by urging Britons to go to the movies. Or in British, go to the cinema. But the closure’s only temporary, so presumably your patriotic visit to the cinema can also be temporary. 

So can your exposure to the Covid virus.

How does going to the movies fit with the world-beating, Covid-containing rule of six that the government keeps explaining to us? As usual it’s simpler than you moaners are trying to make it sound. You can’t get together with more than six people at your house. Or at theirs. Or at the pub. Or outdoors. You can’t mix socially or go to the movies together. But you can go to the movies with, say, twenty-five strangers if you all happen to go to the same show. And if you happened to meet 24 ½ of your closest friends at the movies by accident, that would be okay because the accidental nature of the gathering keeps the virus from spreading. 

Virii are methodical little beasts. Throw a few random moves at them, like running into 24 ½ friends at the movies, and they get confused. Throw popcorn at your friends to remind yourself of what friendship and community used to feel like and the virii will be knocked out of their orbits.

And there’ll be those empty seats between you, which may genuinely help, although more and more evidence is landing on the side of nearly weightless aerosols dancing the virus through the air of enclosed, poorly ventilated spaces, in which case an empty seat may not be enough.

Irrelevant photo: mallow

Masks do help. The question is, will people keep them on in the dark while they eat their popcorn. 

Remember that the rule of six is a guideline, not a law. 

Or maybe it’s a law, not a guideline.

Oh, hell, no one knows anyway. Don’t worry about it. Enjoy the show.

*

Scotland’s Covid app isn’t the same as England’s. It’s called Protect Scotland, and–have I mentioned that the apps have glitches? A man downloaded it, picked up a ping, picked up another ping, and–I won’t take you through all the details–eventually figured out that the app thought he could catch the virus through the floor from the guy downstairs. Who must either levitate or be extremely tall and store his phone on his head to get within two meters of the upstairs phone, which (I’m going to assume) doesn’t live on the floorboards.

Or maybe the neighbor stores his phone on a top shelf. And the downstairs phone does live on the floorboards.

Anyway, I keep reading that the apps have glitches, but I wouldn’t have predicted that one.

*

Speaking of glitches, the one that disappeared some 16,000 positive Covid test results from England’s test and trace system may have been caused by a size limit on the files Excel spreadsheets can accept. Send anything more and it smiles serenely and cuts off whatever’s at the bottom of the file. 

Problem solved, at least from its point of view.

Excel’s habits aren’t news. In 2013, it masked a loss of–oh, something like $6 billion from JP Morgan’s books. So yes, this could’ve been predicted. 

The test and trace contract, by the way, is up for renewal. Given how expensively it’s been screwed up, I’m going to bet they’ll renew it.

*

The Bounce Back scheme, which was supposed to help small businesses survive the pandemic, may have been scammed out of £1.9 billion. The government was warned ahead of time–twice–that it was a vulnerable program but decided to go ahead. 

And Britain’s five biggest banks will make £1 billion out of it. Legally.

Another £238 million will be spent on work coaches to help people who lost their jobs in the pandemic by coaching them on interviews, CVs, and moving into growing sectors. You know growing sectors, like, um, hang on. Work coaching. That’s a field where they’re hiring. 

*

More evidence is landing on the side of Covid not spreading via contaminated surfaces. Scientists aren’t saying it’s impossible, just that it’s not the root of the spread. 

Yes, it’s still worthwhile washing your hands obsessively, and it may be worthwhile disinfecting the groceries and boiling the mail before you so much as look at it, but the real danger is in sharing poorly ventilated spaces with our fellow human creatures. 

 

Covid, the brain, and the toffs: The pandemic update from Britain

The Covid targets targets that we hear most about are the lungs, the liver, the kidneys, and the blood vessels, but some Covid patients also have neurological symptoms, ranging from headaches to confusion to full-out delirium, and evidence is mounting that Covid can attack the brain. 

That’s according to a study posted online and–like most Covid studies in this crisis–not yet peer reviewed. 

Covid isn’t the only virus that does some breaking and entering inside the brain. Zika did, but the body mounted an immune response. Covid, though, is a sneaky little s.o.b., and the body doesn’t seem to notice what it’s doing up there, which is making copies of itself and leaving a trail of destruction. The study found no evidence of an immune response to its presence in the brain.

“Days after infection, and we already see a dramatic reduction in the amount of synapses,” Dr. Alysson Muotri of the University of California said. “We don’t know yet if that is reversible or not.”

Irrelevant photo: Virginia creeper. Photo by Ida Swearingen.

Researchers will need to analyze brain samples from autopsies to see if it’s present in people with milder versions of the disease and in the people who are being called long-haulers, the people whose symptoms hang on and on. A lot of them have a range of neurological symptoms. 

Some 40% to 60% of hospitalized patients have neurological and psychiatric symptoms, but they may not all come from brain infections. Some may come from inflammations throughout the body. So: autopsies.

The problem, though, is that autopsies need people to die first, so this all depends on the right categories of people conveniently keeling over.

Everybody seems to be saying this, but it bears repeating: So much about this disease is still unknown.

*

So what do you do about a disease like that? Well, at a town hall event hosted by the ABC network (that’s a TV channel), Donald Trump told the world that Covid will disappear when everyone develops a herd mentality. 

Conform, people. It’ll save us all.

*

At least in the absence of a vaccine and a herd mentality, testing is the most likely thing to save us, and a new Covid test that’s still in the development stage sounds promising enough to lift even my gloomy spirits. 

Gloomy spirits? Well, I keep telling people that it’s going to be a long winter, then I have an impulse to slap myself silly. I’m sure the other people in question feel the same way. To date, everyone’s good manners have kept the situation from spinning out of control.

But back to the Covid test: Researchers wanted to come up with a quick, accurate test that would be cheap enough for people to test themselves at home every day, and it’s looking promising. 

The test is called STOPCovid, which probably stands for something, since half of it is in caps, and the researchers come from enough U.S. universities that I won’t bother to list them all.

The details of the test involve RNA, magnetic beads, and a high sensitivity, meaning it correctly identifies a lots o’ positive cases. The details are also over my head and I’m going to arbitrarily decide that they’re over yours too, but hey, I’m giving you a link so you can go prove me wrong. 

Actually, it didn’t seem that complicated until I realized that I understood the sentences but not their content. A lot of my life is like that. What I did understand is that it’s promising and that it’s designed to be cheap, fast, and usable. 

Also that it’s not ready yet.

Stay tuned. 

*

The STOPCovid test can’t come fast enough for Britain, because the government’s taken what was already an expensive privatized mess of a testing program and made it worse.

It’s good that in these dark days we’re led by damn fools. 

What’s wrong with the testing program? People are being sent hundreds of miles from home for tests. People with symptoms can’t find tests, meaning they’re left not knowing if they can safely go back to work or if their kids can safely go back to school. 

The head of the test and trace program, Dido Harding (whose background is in business, not public health), explained the disaster by saying that nobody “was expecting to see the really sizable increase in demand.”

Of course not. No one knew schools were reopening or thought that might mean more people being exposed ans needing tests. No one noticed when Boris Johnson nagged everyone who was working from home to go back into the office, which would mean more people getting exposed and needing–yeah, you can see where this is going.

Meanwhile, Jacob Rees Mogg, the leader of the House of Commons, is hailing the testing program as a phenomenal success and telling us all to stop carping about it. 

Me, I’m not carping. I’m a vegetarian. But I will say that the demand for tests is four times greater than the testing capacity.  

All hail the wondrous testing program.

You have to love these people. They have absolutely no shame and minimal contact with reality. Or any desire to contact reality. They caught a glimpse of it once. It involved a lot of people with accents they didn’t like and clothes that cost less than theirs. Not to mention with infinitely less money than they have. It was all very unpleasant and why go through that again?

Anyway, the problems with testing seem to involve a shortage of lab capacity. The labs are also privatized, not that I’m trying to make a point here or anything. 

https://www.bbc.co.uk/news/health-54163226

Meanwhile the number of cases is rising in parts of Britain and people are facing increased localized restrictions. 

Contact tracing’s going well too. Some people working in the system report–anonymously–that by the time they contact people who’ve been exposed to Covid and tell them to isolate themselves for two weeks, more than two weeks have gone by since they were exposed. And this past week, the tracing firm’s software was too embarrassed to go on and some tracers had to be told not to refresh their screens too often. Some of the people they called got so frustrated with how long the calls took that they hung up. 

*

Shall we be completely fair here? The full quote from Jacob Rees-Mogg is, “The issue of testing is one where we have gone from a disease that nobody knew about a few months ago to one where nearly a quarter of a million people a day can be tested, and the prime minister is expecting that to go up to half a million people a day by the end of October.

“And instead of this endless capring, saying it’s difficult to get them, we should actually celebrate this phenomenal success of the British nation.”

All hail the British aristocracy. They either manage to believe this shit or don’t care what they say. 

And somehow or other, they stay in office. No, I can’t explain it either.

Moonshots and international law: It’s the news from Britain 

We all just love good news, which is why we’ll try not to gag when we discuss Boris Johnson’s moonshot plan to test everybody in Britain for Covid all day every day, including when they’re asleep, working in their pajamas, or breaking and entering because they want to wear someone else’s pajamas for a change.

I know, but you do need to let me exaggerate now and then. It prevents explosions.

The moonshot plan is about ramping up Covid testing from 200,000 tests a day to 10 million a day by early next year. It would cost, at a wild and irresponsible guess (sorry–at a sober but preliminary estimate), £10 billion plus. 

Plus how much? At those levels, who cares? By way of comparison, that’s roughly equal to the UK’s education budget, but since the alternative, at least in the scenario posed by the prime minister, is a second lockdown, it’s a bargain at twice the price. 

Or something along those lines. 

Completely relevant photo: Have I mentioned that we’re going to the dogs?

It’ll involve lots of private companies–some of them the same ones who are screwing up the current test and trace program–so I could see where we’d end up paying twice the price. For half the product.

Given that the current testing program is short of something–probably lab capacity but who really knows?–and is therefore suggesting that people drive to hell and back if they seriously want to get tested because Britain’s a small island and when I was a kid we walked to school. Through the snow. We didn’t stand around waiting for a bus to pick us up and moaning about a little rain–

Let’s start that over. Why do you people keep leaving me in charge? 

The moonshot tests, or at least some of them, will give results in minutes. 

The problem is–

No, one of the problems is that the technology to make this work doesn’t exist yet. Another problem is the public health leaders are screaming for more control of the current testing program because the companies running it are making such a mess. 

This time, though, they’ll get it right. And I’ll be twenty again, only much smarter than I was the first time around. 

Also taller.

*

Want another problem with the moonshot program? The government’s advisors weren’t called upon to advise before it was shot at the press. The National Screening Committee was sidelined on the grounds that the moonshot is a testing program, not screening. 

“Mass testing is screening,” according to Allyson Pollock, the director of something very impressive at Newcastle University. I’d give her full title but we need to move on. Sorry.

See how British I’ve gotten in fourteen years? I apologize all the time. I don’t mean it, but I do apologize. 

If I were Britishly British, though I’d write “I’ve got” instead of “I’ve gotten.” Don’t ask me to explain it, but I’ve discovered that the American version annoys the hell out of someone in the village who’s well worth annoying. I’d use it anyway–my speech pattern, c’est moi–but it does add joy to the words.

Where were we? 

If the committee had been involved, it could consider the impact of false positives and false negatives and the social and economic impact of a large number of people being told to self-isolate. 

John Deeks, a professor of something equally impressive at the University of Birmingham said, “There is a massive cause for concern that there is no screening expertise evident in the documents. They are written by management consultants. . . . Before you start, you have to make sure you do less harm than good.”

*

If a massive testing program really happens, is anyone talking about paying people enough that they can afford to stay home if they test positive? 

Don’t be silly. It would set a bad precedent and make people lazy. 

*

While the official testing program limps along, running short of whatever it’s running short of, the University of Exeter is buying its own tests for students and staff–saliva tests that promise results either the same day or the next. They’re made by an outfit called Halo, which says they’re wonderful. As they may well be, but I’d like to hear that from an unbiased source and so far I haven’t found one. With a different test, people who actually understand these things complained that although the company making the test reported that it registered very few false negatives or false positives, it’s possible to game the data and unless companies make their testing process transparent, no one will know if they have. 

I don’t know if Halo’s transparent. 

*

Covid cases have been  rising in Britain, but the number of deaths has stayed low, presumably because the infections are concentrated among younger people, who are less likely to die or be hospitalized. A fair number of fingers have been wagged at them for getting sick. They’ve been out seeing friends, drinking in pubs, eating in cafes, attending illegal raves. 

Of course, the government’s been dangling vouchers in front of them–and the rest of us–to lure us into pubs and cafes so we could support the economy, as well as telling everyone working at home to get out of their bathrobes (which could use a good wash by now anyway) and relocate their hind ends to whatever office it is they used to work in. The economy can’t deal with this many people working from home.

That says something about how much sheer uselessness it takes to keep the economy rolling.

Now that more people are testing positive for Covid, though, it’s their own fault for listening to the government. They should’ve known better. 

Why are younger people really picking up the disease? A combination of factors, probably. Many of them have jobs that put them into contact with the public, and with all the viruses the public carries. Some of them are careless. They’ve been told they’re unlikely to get seriously sick. The police have broken up some illegal raves, but the entire younger population of the country wasn’t at them, 

You also have to figure that a lot of us who are retired are still in hiding, or semi-hiding, so we’re a little harder for the germs to find. Opportunists that they are, they jump into whoever they find.

What’s the government’s advice to  keep young people on the straight and narrow? “Don’t kill granny.”

Seriously.

There’s something unnerving about that as a way of mobilizing a nation.

*

No news from Britain is complete without a mention of Brexit: 

Rod McKenzie of Britain’s Road Haulage Association warns us, or warns the government, or warns anyone who’s listening, which may not be anyone at all since the government listens only to itself, I don’t really exist, and we’re not so sure about you–

Can we start that over?

Rod McKenzie, of Britain’s Road Haulage Association, warns us that we’re “sleepwalking to a disaster with the border preparations that we have, whether it is a deal or no-deal Brexit at the end of December.”

He’s worried about supply chains being interrupted, especially on the heels of the Covid crisis. 

“The difference here is between a disaster area and a disaster area with rocket boosters on.”

Remember the beginning of lockdown, when everyone was stocking up on toilet paper and bread flour (or hoarding it, depending on whether we were talking about ourselves or our neighbors)? If you’re in Britain, it might be worth doing that again. I have a recipe that calls for both if you want it.

Brexit, Covid spikes, and lies: It’s the news from Britain

Britain is gearing up to break international law in “a very limited and specific way,” according to Brandon Lewis, the Northern Ireland secretary. 

Last October, Boris Johnson’s government negotiated a withdrawal agreement with the European Union that would avoid a hard border between Ireland and Northern Ireland, something everyone with half a brain and no political advisors with the initials D.C. considers important because a hard border threatens to reignite the Troubles in Northern Ireland. We’ll skip the background there because it’s long and complicated. If you’re not up on it, just nod sagely and pretend you know what I’m talking about. 

It was a patched-together agreement and even at the time it looked unworkable because if Britain left the EU there had to be a hard border somewhere, and if it wasn’t going to be between Ireland and Northern Ireland, then it was going to be in the middle of the Irish Sea, pushing Northern Ireland away from the rest of the UK. 

Wave bye-bye to the nice island, Boris. 

Look! It’s waving back. 

Or maybe that’s Northern Ireland waving hello to the Irish Republic. Either way, aren’t the Irish friendly?

Irrelevant photo: a red hot poker.Not an actual one, you understand. A flower that goes by that name.

Anyway, it was all going to be okay, we were told, because they–they being some unnamed genius in a governmental office somewhere, whose initials were probably D.C.–would figure out a way to make it work.

So what have they figured out? Well, um, nothing. Which is why we’re gearing up for that limited and specific little law-break, Your Honor. See, we were painting the floor. And then we realized we were in a corner and surrounded by wet paint. And we really needed a beer, and on top of that, we had to pee.

Sorry, did I just say pee? We needed to visit the loo and drive to Barnard Castle to test our eyesight. But you understand the difficulty, right?

Sorry: British political in joke implanted there. I couldn’t help myself. It all has to do with a prime ministerial advisor who doesn’t believe laws apply to him.

The former prime minister Theresa May asked how the government planned to “reassure future international partners that the UK can be trusted to abide by the legal obligations of the agreement.” And you know what, no one answered her. Because she’s the former prime minister, not the current one.

Somewhat more noticeably, the most senior legal civil servant resigned over it, and that seems to be creating a few shock waves. He’d advised ministers–or so Westminster gossip (which I get by way of the newspapers) holds–that the changes would be illegal, and since civil servants are required to stay within the law, he quit.

That raises the question of whether the justice secretary and attorney general, who take oaths to uphold the rule of law, will find themselves in deep shit at some point over this.

The government’s said to have asked for independent legal advice and when they didn’t like what the advice advised are said to have ignored it. 

Senior Tories are urging the government to perform yet another U-turn–a maneuver the government does well. The question is, how many senior Tories are we talking about, and how many junior ones? The Tories have a majority of 80, so it’ll take more than a handful to have an impact.

Please ensure that your seat belts are securely fastened. We’re headed for turbulence.

*

Britain’s had a spike in Covid cases and is imposing new restrictions to try to stop it. Or to slow it down. Or to be seen to be doing something while still trying to get people who’ve been working at home back into the office so they can support the economy by buying sandwiches and expensive coffees and those sparkly notebooks that eight-year-olds like. Without those sales, the economy’s sinking.

Whatever. We now have new restrictions. 

In England, starting on Monday, social gatherings of more than six people or from more than two households will be illegal. Unless they’re weddings or funerals or organized team sports. Or schools or work, which aren’t exactly social but the health secretary Matt Hancock mentioned them anyway because he was trying to make the point that the ”the rule is really simple.” 

“What,” a friend asked me as I was explaining how simple this is, “about my brother, who has six kids?”

“Well,” I said, “he should’ve thought of that before he had them.” 

And just so I’d sound all British about this, I added, “Shouldn’t he?”

As it turns out, it really is simple. It’s either six people from any number of households (two households, six households, thousands of households if you can make the numbers work) or any number of people from any two households. Plus either a dessert or an appetizer.

Fizzy drinks and alcohol cost extra. And my friend’s brother can keep all his kids. 

Of course, the rules are different if you’re in one of the cities and towns that have local lockdowns or the restrictions that are an attempt to avoid a full-out lockdown. No two local rules seem to be the same. In some, restrictions involve venues–however the hell they’re defining that–having to close between 10 pm and 5 am, which is when the virus is known to come out and play. In others, you can’t have people over, indoors or in your garden, which in American is called a yard, unless you’ve formed a support bubble, which is created when a household with one adult joins another household and when they add soap to a dishpan of water (glycerine helps) and have a bubble pipe or wand. 

It’s best to do this outdoors, because it’s messy.

With the emphasis on gardens, it sounds like you could get together if you put a fence between one household and the other as long as no more than six people are inside the fence.

Anyway, it’s really very simple. 

I’ve always considered the mess an art form. I should idolize Hancock, but somehow he just doesn’t do it for me. 

All of that, of course, only applies to England. What about in Scotland, Wales, and Northern Ireland (if it hasn’t floated out of sight yet)?

It’s simple, so I’ll quote the BBC to be sure I get it right:

  • In Scotland, up to 15 people from five different households can meet outdoors.
  • In Wales, up to 30 people are allowed to see each other outdoors.
  • In Northern Ireland, the maximum number of people who can meet outdoors has been reduced from 30 to 15.

However, if we’re talking about being indoors, either at your place or in a pub, the rules alllow:

  • In Scotland, up to eight people from three different households
  • In Northern Ireland, up to six people from two households
  • In Wales, up to four households can form an “extended household.”

I don’t know how it can get any clearer than that. But keep in mind that the distance you’re supposed to keep from other people will vary depending on whether you’re in England, Wales, Scotland, or Northern Ireland. Because the virus behaves differently depending on the accent it hears.

*

I can’t think why I’m so tired.

*

Last week sometime, I told you my tale about trying to get one of Britain’s world-beating Covid tests and being advised to go from Cornwall to Wales. I’m used to being told where to go, and it doesn’t usually involve anyplace as nice as Wales, so I didn’t get my feelings hurt. 

But now it turns out that I’m the reasons Britain is short of Covid testing materials, and that does hurt my feelings. 

Matt Hancock, our secretary of state for health, social care, and public excuses, tells us the shortage of Covid tests is the fault of people getting tested when they don’t need a test. A full 25% of the people asking for tests turn out to be this sort of me-too-ers. They don’t have the symptoms, so what are they up to? 

We’ll get to that, but first let’s talk about symptoms. The government web site gives you a choice of three, but if you bump around the internet, limiting yourself to entirely responsible sites, you’ll find that the virus is more generous than that. You can have five symptoms if you want them. You can probably have more than that, but I’m prone to dizziness when I work with higher numbers so I stopped there.

But even if the government could count to five, it shouldn’t matter whether you have symptoms. One of the things that makes the virus so damn hard to stamp out is that asymptomatic people can and do transmit it. Any chance of controlling it rests on (a) a highly effective vaccine, (b) magic, or (c) testing–lots and lots of testing, including testing people who don’t have any symptoms so they can find out if they’re carrying it and then isolate themselves and not pass it on. 

Let’s pause here for some advice: If you have an off-brand symptom and want to get tested, you should lie. Don’t worry. This is a government that understands lying. 

*

Trials for the Oxford/AstraZeneca Covid vaccine hit Pause when a participant was hospitalized with what may be a serious reaction to the vaccine and may be something unrelated. You know, the kind of thing that happens when a satellite flies over your house just as you’re chewing bubble gum and the cat’s litter tray needs cleaning and you’ve got Billie Holiday playing on whatever on earth it is you use to play recorded music these days. And–I almost forgot–you breathe in a virus that isn’t the one we’re concerned about but does still make you very, very sick.

These things do happen and you can’t know in advance what effect they’ll have. Researchers are trying (frantically, I’d think, but we all know I’m not there, so let’s not take me too seriously) to figure out if the participant’s illness is related to the vaccine or not. It may not be, but this is why political pressure to shorten the testing process is really very stupid.

Standardization and movable goal posts: It’s the pandemic news from Britain

Earlier this year, in a King Kong meets Godzilla moment, Covid-19 ate the end-of-year standardized tests that older Britain’s students would normally have taken. For kids who were applying to universities, that meant–ack!–they had no test grades to submit. 

But they didn’t have no grades at all, because every year teachers estimate the grades their students can expect to get on the standardized tests, and kids submit those with their applications. Then they take the tests and submit the actual scores, which (or so I’ve read) are on average lower than the predicted grades. 

So what’s a sober, responsible education system to do when the actual tests can’t be taken? Why, make up a system as it goes along, of course. 

Scotland ran up against this first, since (limited) power over the schools has been devolved to the governments of Scotland, Wales, and Northern Ireland. Scotland’s solution was to use an algorithm–because algorithms are fair, unbiased, don’t run for office, and don’t leave crumbs under their desks–to compare students’ predicted grades with the grades students from their schools got in previous years and with the lifecycle of the common earthworm. After the algorithm had ruminated for microseconds, it spit out corrected grades for everyone.

Irrelevant photo. Montbretia, a flower that spreads like mad and chases gardeners through their dreams.

And what happened? Lo and behold, the poorer (or in other ways the more disadvantaged) the families of the kids you went to school were, the more points you lost. Because guess what: Kids from your school just don’t do that well on standardized tests, so be realistic, you wouldn’t have either. 

All predictable hell broke loose, and the Scottish government backed down. The predicted grades will stand.

Then the hot potato was thrown to England, Wales, and Northern Ireland

How can you throw a hot potato simultaneously to three countries? Through the magic of privatization, that’s how. Our politicians can make one potato into three and lower taxes on corporations and the richest 1% all at the same time.

Okay, I’ll come clean: Privatization has nothing to do with this. I just slipped it in because I like to blame things on privatization. And I’m right often enough that the habit gets reinforced. See below.

England is saying students can accept the grades “based on teacher estimations” (there’s a lot of wiggle room in there, so I’m relying on quotation marks to keep everything in place), or swap them for the marks they got on their mock exams. Or they can take the test in the fall. 

Assuming that reality doesn’t intervene and cancel the tests again, although no one seems to be talking about that, at least not publicly.

Of course, that means this coming academic year goes straight into the trash.

Head teachers (if you’re American, read that as principals), though, are saying that mock exams aren’t graded in any consistent way. And some schools canceled mock exams when they saw the pandemic headed for them, so their kids have none to fall back on.

Wales says its modeling is fair, and nearly half of its student grades are based on AS levels. AS levels are a related test taken earlier that I’m not going to try to explain because, c’mon, I don’t really understand this stuff either. Just nod soberly and no one will know how lost you are. 

Northern Ireland is saying it’ll let students appeal their grades on the basis of their mock exam scores. 

I can’t explain why universities aren’t stepping up and saying, “We’re not taking any of this seriously and we’ll be making our own judgements on the basis of [fill in the blank].” Maybe there’s nothing to slot into that blank. I’m too distant from the British educational system to tell you anything useful. You can almost hear them getting ready to say, “Nothing to do with me, your honor.”

Everyone who writes about this is required to use the phrase moving the goal posts. So think of Britain as a country of four nations (which aren’t necessarily getting along well at the moment), and in each of those nations two people are running and random directions, struggling to keep goal posts upright and the space between them more or less even, because if you lose that relationship they’re not goal posts anymore, they’re just posts.

*

So much for the kids (or former kids) who’ve graduated. Let’s turn our jaded attention to the kids who are due back in school: Summer’s winding down and the government’s hell bent to get them back into the classroom. Because education matters and a generation is in danger of being lost. Because (somewhat less nobly) parents can’t go back to work until their kids can be safely stashed someplace. Because (still less nobly than that) the nation’s sandwich and coffee shops can’t sell sandwiches and coffee until office workers are poured back into their cubicles and deskicles. Without people pouring in and out of buildings, city centers are dying.

Spellcheck, in case you’re interested, doesn’t object to the word deskicle. What’s on earth has happened in the working world since I left? Are people really working at deskicles?

Schools will be safe, the government tells us. The kids will wash their hands and magical incantations will be both incanted and decanted over the school grounds at the start of each school day. Five-year-olds will be reminded every hour on the hour not to touch anything.

Oh, hell, don’t worry about the details. It’ll be fine.

And while that’s being released to the press, what should happen but that a couple of new bits of information appear, from the U.S. and Israel, about kids and the virus.

From a summer camp in Georgia comes the news that younger kids get infected as well as older ones. As the Center for Disease Control so poetically put it, “The findings demonstrate that Sars-CoV-2 spreads efficiently in a youth-centric overnight setting, resulting in high attack rates among persons in all age groups, despite efforts by camp officials to implement most recommended strategies to prevent transmission. . . .

“This investigation adds to the body of evidence demonstrating that children of all ages are susceptible to Sars-CoV-2 infection and, contrary to early reports, might play an important role in transmission.”

Israel had been fairly effective in clamping down on the virus, but in May it reopened its schools. By the end of the month, it had closed a hundred of them and ordered thousands of students and staff to quarantine. 

Epidemiologist William Hanage said, “If community transmission is low, the costs to kids of keeping schools closed are much greater than keeping them open.

“However if community transmission is high or increasing, opening schools can only add to it. It’s not clear by how much.” 

So nothing’s certain yet, but the reports are sobering. 

What does the government tell us? The education secretary, Gavin Williams, said on Monday that opening the schools carried few risks. And Public Health England, having apparently said in an unpublished study that older kids were more likely than younger ones to get and transmit the disease, publicly said that reports that it has recommended tougher rules for older kids were incorrect. Also wrong. And false. Did I mention false? 

“Parents can be reassured that to [blah blah blah] an extremely stringent system of controls by” et cetera. Also and so forth. 

It’ll all be fine. 

*

A health minister, Edward Argar, told the world (or as much of it as was listening) that Britain’s system of tracing the contacts of infected people is almost as good as New Zealand’s

“We’ve traced a quarter of a million in the space of about two and half months . . .” he said. “Look at New Zealand, they have a slightly higher percentage success rate, they’ve traced 360 people.

New Zealand’s population is 4.8 million. England’s is 56 million. Last I checked, New Zealand had had a total of 1,570 cases compared to England’s 270,000. So yeah. We’re hardly behind them at all.

On the other hand, New Zealand has 26.7 million sheep.

Argar–and this, of course, is no more relevant than the sheep or the photo I dropped in at the top this post–is a former lobbyist for Serco, which runs the £108 million test and trace system. The system that only managed to contact a little over half the people in the same household as folks who’d tested positive. 

In the same household. They’d do a better job if they called the sheep.

Someone has leaked a memo from Public Health England in which they approached Serco about the test and trace contract. No bids were taken from other companies.

But it’s worth mentioning that Argar has also served in the Justice Department, and that Serco runs five private prisons and a prisoner escort service. The justice secretary, David Gauke, felt he needed to reassure the world at large that there wouldn’t be any conflict of interest.

So settle down, cynics of the world. It’s all in good hands.

My thanks to Bear Humphries and Annie Robinson for letting me know about the esteemed Mr. Argar.

*

What’s the story on Russia’s vaccine? Skeptics point out that they’ve skipped phase III trials–the ones that look for side effects and measure its effectiveness, preferably in the widest possible sample of the population. The phase that generally takes months. 

So it’s not clear either how safe or how useful the vaccine will be. Russian officials say they hope its antibody response will last for as long as two years. Skeptics point out that no one knows much about how long Covid antibodies last or what protection they offer, and they worry that a partially effective vaccine could lead governments and people to abandon efforts to suppress the virus. 

Professor of immunology Danny Altmann said, “The collateral damage from release of any vaccine that was less than safe and effective would exacerbate our current problems insurmountably. . . . We are all in this together.”

Vladimir Putin’s daughter has taken a dose. Make of that what you will.

The pandemic news from Britain, with a side of cultural appropriation

With English schools set to reopen in September, the papers are crammed with discussions about the safety of kids, of their families, and of school staff during the pandemic. Scotland, Wales, and Northern Ireland make their own rules on this, so let’s keep it simple by pretending we’ve never heard of any of them. We’ll focus on England’s schools and preparations. Or lack thereof.

Education Secretary Gavin Williamson said there’s not much evidence of the virus being transmitted in schools. Education Secretary Gavin Williamson has–hang on; I’m looking for a diplomatic way to say this–his head up his ass. But when you’re part of a government like the current one, that’s sometimes the best place to keep it, so we can’t entirely blame the man. 

As far as I can figure out, the evidence on how readily kids transmit the virus isn’t clear. Here’s what I think I know. Emphasis on think.

Irrelevant photo: Cotoneaster–pronounced kuh-tone-ee-ASS-ter, not cot-ton-EAST-er. The mysteries of English spelling.

One outbreak in a French high school ended up with 38% of students, 43% of teachers, and  59% of the non-teaching staff being infected. But a primary school in the same city had a much lower rate of infection in both students and staff. But don’t worry, Gavin. All of that happened in French and French isn’t a required subject, so we don’t need to worry about it.

Older kids seem to transmit it more often than younger ones. No one is sure why, since young kids, cute as they are, are usually little germ factories. It might be because younger kids are less likely to get sick, so they’re less likely to cough and sneeze. It also might not be. 

Before anyone sorts out how extensively younger kids transmit the virus, we need a better understanding of who’s catching it from who. Or from whom, if you want to be like that. The studies indicating that young kids don’t transmit it widely are still pretty limited.

There’s some discussion of opening schools and counterbalancing that by closing pubs and restaurants. The idea is to trade one place of transmission for the other, keeping the overall national rate the same.

Possibly.

The Association of School and College Leaders said that in the absence of clear guidance from the government, schools are making their own plans.

*

Why don’t younger kids catch Covid more often? One theory is that the ACE2 receptors that Covid uses to invade the lungs haven’t developed much in young kids. (Don’t I sound like I know what I’m talking about here?) But then kids get older and wiser and they make more of those nifty little receptors, because hey, that’s what grownups do, and in marches the virus until, lucky them, they have enough that they can get sick too.

Remember when we all taught ourselves to smoke because it made us look grown up? We never seem to learn, do we?

*

Would it help control the virus if staff and students were tested regularly once the schools reopen? Possibly, but the schools minister, Nick Gibb, said the government’s not going to do it. They’ll stick to testing people with symptoms. Because that’s the way they’re going to do it and by god it will work. 

*

But forget about the schools for a minute. Let’s talk about England’s world-beating test and trace system. It’s laying off 6,000 people.

Take that, world.

While the world lies on the mat recovering and the umpire counts, let me explain: The track and trace system was centralized and contracted out to mega-companies who know zilch about public health. It’s generated reports of people having been hired, minimally trained, and then given next to no work. It hasn’t done well at tracing the contacts of people who test positive for the disease. 

The contact tracers who haven’t been canned will now be assigned to work with local public health teams, who have a much better success rate and who (I’m speculating here) might offer them some training, since they actually know a bit about public health. 

*

We are, of course, all hoping for a vaccine that will make the rest of this nonsense irrelevant, which is a nifty lead-in to this next item: The trials of the Oxford and Moderna vaccines could be undermined by too monochrome a test group. The Oxford trial group was only 1% black and 5% Asian. In Moderna’s test group–and here I have to shift from percentages to numbers because that’s what the article I’m linking to did and I’m too numerically incompetent to shift them over myself, although mixing them is senseless and makes comparison harder–40 of the 45 participants were white. 

As researcher and surgeon Oluwadamilola Fayanju of Duke University explained it, “Diversity is important to ensure pockets of people don’t have adverse side-effects.”

Anyone who’s still countering Black Lives Matter by saying that all lives matter, please take in the implications of that. It might help explain why the focus is on black lives just now.

Based on the numbers, I think we’re talking about the safety trials there, not the larger ones that test for effectiveness.

*

Best of luck with that link, by the way. Several publications–New Scientist, the BBC, the Guardian–keep ongoing pandemic updates. They’re incredibly useful, but I’m never sure that the link I drop here will take anyone to quite the place where I found the information. 

*

It must be time for a non-Covid break here. We’ve been almost serious for long enough to have earned one.

A couple of Canadian businesses thought they’d swipe a bit of the Maori language to make their products look cool. Which is how a brewery and a leather store ended up naming their ale / entire outlet Pubic Hair–or huruhuru, in te reo Maori, the Maori language. 

The brewery’s cofounder said he thought huruhuru meant feather. 

To be fair–and I am sometimes–huruhuru has a number of meanings, and feather is one of them. I don’t speak Maori, but I’ve brushed up against it enough to wonder if everything doesn’t have a number of meanings. But according to  TeHamua Nikora, who used Facebook to explain the problem, the first thing Maori speakers will think of when they see the brand is not going to be feather. 

“It’s that entitlement disease they’ve got,” he said. “Stop it. Use your own language.” 

*

Heinz, on the other hand, was using its own language when it named its combined ketchup-mayonnaise Mayochup, but it put its foot in it anyway. Cree speakers went on–what else?–Twitter to say that in Cree that means shit-face.

Enjoy your burger.